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Glyoxylic Acid → 4-Hydroxyphenylglycine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Glyoxylic Acid | HCID 760 | — |
| 反応物 | Phenol | HCID 996 | — |
| 反応物 | Ammonium Acetate | HCID 517165 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 4-Hydroxyphenylglycine | HCID 92143 | 28.9% |
反応手順
30 g of an aqueous 40% glyoxylic acid solution are added to 70 ml of water, and 37.5 g of ammonium acetate and 22.5 g of phenol are added thereto under stirring. The mixture is stirred at room temperature for 41 hours. The crystalline precipitates are collected by filtration under cooling, and then successively washed with water and methanol. 7.8 g of DL-p-hydroxyphenylglycine are thereby obtained as white crystals. Yield: 28.9%, M.p. 225°-228° C. (decomp.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04175206 |
| 出典データセット | uspto-grants-1979_11 |
| ORD ID | ord-4a71fba6378949a183990fe45aff8c26 |
| 出典メモ | uspto-grants-1979_11 |