Hydrochloric Acid → 4-Chloro-2-fluoroaniline

HRID 47005

反応式

HRID 47005 の反応式
[Cl:1][C:2]1[CH:11]=[CH:10][C:5]([NH:6]C(=O)C)=[C:4]([F:12])[CH:3]=1.Cl>C(O)C>[Cl:1][C:2]1[CH:11]=[CH:10][C:5]([NH2:6])=[C:4]([F:12])[CH:3]=1

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 8531744'-Chloro-2'-fluoroacetanilide

生成物 1

HCID 938984-Chloro-2-fluoroaniline

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

A mixture of 119 parts of 4'-chloro-2'-fluoroacetanilide in 475 parts of ethanol and 200 parts of 37% hydrochloric acid was refluxed for 17 hours and the solvent removed at a reduced pressure of 300 mm.Hg to yield the moist, solid hydrochloride salt of 4-chloro-2-fluoroaniline.

後処理

  1. temperaturewas refluxed for 17 hours
  2. customthe solvent removed at a reduced pressure of 300 mm.Hg

出典と根拠

ORDレコード
ord-ebdbfc73549c44b5b2abb8ac1aa4e104
出典データセット
uspto-grants-1979_11
特許番号
US04175948

関連ノート

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