Methanol → Methyl 3,4-dimethoxycinnamate

HRID 470618

反応式

HRID 470618 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]=[CH:12][C:13]([OH:15])=[O:14])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[CH3:16]O>S(=O)(=O)(O)O>[CH3:16][O:14][C:13](=[O:15])[CH:12]=[CH:11][C:5]1[CH:6]=[CH:7][C:8]([O:9][CH3:10])=[C:3]([O:2][CH3:1])[CH:4]=1

参加物

4

反応物 2

HCID 887MethanolHCID 168483',4'-Dimethoxycinnamic acid

生成物 1

HCID 94307Methyl 3,4-dimethoxycinnamate

試薬・触媒・溶媒 1

HCID 1118Sulfuric Acid溶媒

実験手順

3-(3,4-Dimethoxy-phenyl)-acrylic acid (compound of Example 2 (Step 1); 1.0 g, 4.8 mmol) was dissolved in methanol (10 mL) in the presence of catalytic amount of sulfuric acid. The reaction mixture was stirred at room temperature for 4 h. The reaction mixture was cooled at 5° C. and quenched with saturated sodium carbonate solution (2 mL). The solid obtained was filtered and dried.

後処理

  1. temperatureThe reaction mixture was cooled at 5° C.
  2. customquenched with saturated sodium carbonate solution (2 mL)
  3. customThe solid obtained
  4. filtrationwas filtered
  5. customdried

出典と根拠

ORDレコード
ord-0389e983858e4fde970403772b1e0438
出典データセット
uspto-grants-2014_01
特許番号
US08629277B2

関連ノート

読み込み中…