1,5-Anhydro-2,3,4-trideoxy-2-[[(1,1-diMethylethoxy)carbonyl]aMino]-D-erythrohexitol → HCID 86672604、化合物

HRID 470689ノート

反応式

HRID 470689 の反応式
C(OC([NH:8][C@@H:9]1[CH2:14][CH2:13][C@@H:12]([CH2:15][OH:16])[O:11][CH2:10]1)=O)(C)(C)C.[ClH:17].O1CCOCC1>CO>[ClH:17].[NH2:8][C@@H:9]1[CH2:14][CH2:13][C@@H:12]([CH2:15][OH:16])[O:11][CH2:10]1

参加物

4

反応物 2

HCID 109880991,5-Anhydro-2,3,4-trideoxy-2-[[(1,1-diMethylethoxy)carbonyl]aMino]-D-erythrohexitolHCID 204431481,4-Dioxane hydrochloride

生成物 1

HCID 86672604HCID 86672604、化合物収率 100%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

1,5-Anhydro-2-[(tert-butoxycarbonyl)amino]-2,3,4-trideoxy-D-erythro-hexitol (Eur. J. Org. Chem., 2003, 2418-2427) (6.00 g, 0.03 mol) was dissolved in methanol (20 ml), 4N hydrochloric acid/1,4-dioxane solution (60 ml) was added and the resulting mixture was stirred at room temperature for 1 hour. The reaction solvent was evaporated under reduced pressure to give 4.5 g (100%) of the title compound as a colorless solid.

後処理

  1. customThe reaction solvent was evaporated under reduced pressure

出典と根拠

ORDレコード
ord-91fad848ad0d4a8a9e383f56c694abbb
出典データセット
uspto-grants-2014_01
特許番号
US08629133B2

反応ノート

読み込み中…