化工社化工社 化学情報印刷レポート · 研究参考用
1-Piperazinecarboxylic acid, ethyl ester → 5,6-Dimethoxy-3(4-carbethoxy piperazino)methylene oxindole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Piperazinecarboxylic acid, ethyl ester | HCID 8431 | — |
| 反応物 | HCID 178486553 | HCID 178486553 | — |
| 生成物 | 5,6-Dimethoxy-3(4-carbethoxy piperazino)methylene oxindole | HCID 54095422 | — |
反応手順
4.0 g. of 5,6-dimethoxy-3-hydroxymethylene oxindole was reacted with N-carbethoxy piperazine as described in Example 2, except that 0.10 g. toluene sulfone acid was added as a catalyst. Yield, 3.05 g. of product, m.p. 172°-174° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04176191 |
| 出典データセット | uspto-grants-1979_11 |
| ORD ID | ord-f04b5cd13a0348399248d9d826df7a49 |
| 出典メモ | uspto-grants-1979_11 |