2,6-Anhydro-5-[(tert-butoxycarbonyl)amino]-3,4,5-trideoxy-L-erythro-hexonic acid → HCID 86672605、化合物
反応式
[ClH:1].O1CCOC[CH2:3]1.C(OC([NH:15][C@H:16]1[CH2:24][O:23][C@H:19]([C:20]([OH:22])=[O:21])[CH2:18][CH2:17]1)=O)(C)(C)C>CO>[ClH:1].[NH2:15][C@H:16]1[CH2:24][O:23][C@H:19]([C:20]([O:22][CH3:3])=[O:21])[CH2:18][CH2:17]1参加物
4
実験手順
4N hydrochloric acid/1,4-dioxane solution (20 ml) was added to a methanol (5 ml) solution of 2,6-anhydro-5-[(tert-butoxycarbonyl)amino]-3,4,5-trideoxy-L-erythro-hexonic acid (Eur. J. Org. Chem., 2003, 2418-2427) (1.00 g, 4.08 mmol) at room temperature and the resulting mixture was stirred for 20 hours. The reaction mixture was concentrated under reduced pressure to give 0.80 g (100%) of the title compound.
後処理
- concentrationThe reaction mixture was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-5fcc9d1e4e9c42ce8a79ad673fc73def
- 出典データセット
- uspto-grants-2014_01
- 特許番号
- US08629133B2
反応ノート
読み込み中…