3-(Dimethylamino)propyl chloride hydrochloride → 7,7-Dimethyl-2-phenyl-5-(3-dimethylamino-propyl)-5H,7H-imidazo[4,5-h]isoquinoline-4,6-dione dihydrochloride
反応式
[ClH:1].[CH3:2][C:3]1([CH3:24])[C:12](=[O:13])[CH:11]2[C:6](=[C:7]3[N:17]=[C:16]([C:18]4[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=4)[N:15]=[C:8]3[C:9](=[O:14])[CH2:10]2)[CH:5]=[N:4]1.Cl.[CH3:26][N:27]([CH3:32])[CH2:28][CH2:29][CH2:30][Cl:31]>>[ClH:31].[ClH:1].[CH3:2][C:3]1([CH3:24])[C:12](=[O:13])[CH:11]2[C:6](=[C:7]3[N:17]=[C:16]([C:18]4[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=4)[N:15]=[C:8]3[C:9](=[O:14])[CH:10]2[CH2:30][CH2:29][CH2:28][N:27]([CH3:32])[CH3:26])[CH:5]=[N:4]1参加物
3
実験手順
Prepared analogous to Example 23 from 3.4 gm of 7,7-dimethyl-2-phenyl-5H,7H-imidazo(4,5-h]isoquinoline-4,6-dione hydrochloride and 1.7gm of 3-dimethylamino-propyl chloride hydrochloride (reaction temperature: 50°-60° C.; reaction time: 18 hous).
出典と根拠
- ORDレコード
- ord-861f45d8930049aebc72cc5caecb3e47
- 出典データセット
- uspto-grants-1979_11