2,2,4-Trimethyl-1,3-pentanediol → 2-(3-Hydroxy-2,2,4-trimethylpentyloxy)-6-nitrobenzonitrile

反応式

[CH3:1][C:2]([CH3:10])([CH:5]([OH:9])[CH:6]([CH3:8])[CH3:7])[CH2:3][OH:4].[N+:11]([C:14]1[CH:21]=[CH:20][CH:19]=[C:18]([N+]([O-])=O)[C:15]=1[C:16]#[N:17])([O-:13])=[O:12]>>[OH:9][CH:5]([CH:6]([CH3:8])[CH3:7])[C:2]([CH3:10])([CH3:1])[CH2:3][O:4][C:18]1[CH:19]=[CH:20][CH:21]=[C:14]([N+:11]([O-:13])=[O:12])[C:15]=1[C:16]#[N:17]

参加物

反応物 2

HCID 89462,2,4-Trimethyl-1,3-pentanediol

HCID 520718Dinitrobenzonitrile

生成物 1

HCID 673992382-(3-Hydroxy-2,2,4-trimethylpentyloxy)-6-nitrobenzonitrile収率 90%

実験手順

Prepared as in Example 215c from 2,2,4-trimethylpentane-1,3-diol and 2,6-dinitrobenzonitrile in 90% yield. MS 293 (MH+).

出典と根拠

ORDレコード: ord-e468c37b4e2544daa55e686d79c5f845
出典データセット: uspto-grants-2014_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US08633186B2

反応ノート

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