化工社化工社 化学情報印刷レポート · 研究参考用
1,8-Diazabicyclo(5.4.0)undec-7-ene → 1-Chloro-4-[(3-ethyl-4-methoxybenzyl)amino]-6-phthalazine carbonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| 反応物 | 1,4-Dichlorophthalazine-6-carbonitrile | HCID 10656738 | — |
| 反応物 | 3-Ethyl-4-methoxybenzylamine hydrochloride | HCID 22744626 | — |
| 溶媒 | N-methyl-2-pyrrolidone | HCID 13387 | — |
| 生成物 | 1-Chloro-4-[(3-ethyl-4-methoxybenzyl)amino]-6-phthalazine carbonitrile | HCID 18374611 | — |
反応手順
1,4-Dichlorophthalazine-6-carbonitrile and 3-ethyl-4-methoxybenzylamine hydrochloride were stirred at room temperature in 1-methyl-2-pyrrolidinone in the presence of DBU, whereby 1-chloro-4-[(3-ethyl-4-methoxybenzyl)amino]-6-phthalazine carbonitrile was obtained as a less polar compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06699870B2 |
| 出典データセット | uspto-grants-2004_03 |
| ORD ID | ord-c446d2ee67c04b3bb954cb226a32f0d4 |
| 出典メモ | uspto-grants-2004_03 |