1336910-19-0 → HCID 67465671、化合物
反応式
[CH2:1]([O:3][C:4]([C:6]1([F:13])[CH2:11][CH2:10][CH2:9][NH:8][C:7]1=[O:12])=[O:5])[CH3:2]>C(O)C>[F:13][C@@:6]1([C:4]([O:3][CH2:1][CH3:2])=[O:5])[CH2:11][CH2:10][CH2:9][NH:8][C:7]1=[O:12]参加物
3
試薬・触媒・溶媒 1
実験手順
Samples were prepared in batches according to the following method: ethyl-3-fluoro-2-oxo-3-piperidinecarboxylate (25 g) was dissolved in ethanol (450 ml) with gentle heating and sonication. The solution was then filtered through a Pall Acrodisc 37 mm syringe filter with 1 μm glass fibre membrane to remove fines and undissolved material. The filtered solution was adjusted to a total volume of 500 ml with ethanol to give a solution with nominal concentration of 50 mg/mL.
後処理
- customSamples were prepared in batches
- temperaturewith gentle heating
- customsonication
- filtrationThe solution was then filtered through a Pall Acrodisc 37 mm syringe
- filtrationfilter with 1 μm glass fibre membrane
- customto remove fines and undissolved material
- customto give a solution with nominal concentration of 50 mg/mL
出典と根拠
- ORDレコード
- ord-8c45197d316a4a7b93b250bf2246a7b8
- 出典データセット
- uspto-grants-2014_01
- 特許番号
- US08633319B2
反応ノート
読み込み中…