化工社化工社 化学情報印刷レポート · 研究参考用
Trifluoroacetic acid → 1,3-Dichloro-5,6,6a,7,8,12b-hexahydrobenzo[k]phenanthridine-6-carboxylic acid ethyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Trifluoroacetic acid | HCID 6422 | — |
| 反応物 | 1,2-Dihydronaphthalene | HCID 9938 | — |
| 反応物 | 3,5-Dichloroaniline | HCID 12281 | — |
| 反応物 | 2-Ketobutyrate | HCID 3593277 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | 1,3-Dichloro-5,6,6a,7,8,12b-hexahydrobenzo[k]phenanthridine-6-carboxylic acid ethyl ester | HCID 10199516 | 85% |
反応手順
Compound 12 was prepared in a yield of 85% by the basic process from 5.0 mmol 3,5-dichloroaniline, 5.5 mmol ethylglyoxalate solution (50% toluene), 15.0 mmol 1,2-Dihydronaphthalene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06699877B2 |
| 出典データセット | uspto-grants-2004_03 |
| ORD ID | ord-3d54656f7e5948219183190a4e02e3bf |
| 出典メモ | uspto-grants-2004_03 |