Tetrafluoroboric acid → 5-Bromo-2-methylbenzenediazonium tetrafluoroborate

HRID 473781

反応式

HRID 473781 の反応式
[N:1]([O-])=O.[Na+].[CH3:5][C:6]1[CH:12]=[CH:11][C:10]([Br:13])=[CH:9][C:7]=1[NH2:8].[F:14][B-:15]([F:18])([F:17])[F:16].[H+]>O>[F:14][B-:15]([F:18])([F:17])[F:16].[Br:13][C:10]1[CH:11]=[CH:12][C:6]([CH3:5])=[C:7]([N+:8]#[N:1])[CH:9]=1

参加物

5

反応物 3

HCID 28118Tetrafluoroboric acidHCID 27348055-Bromo-o-toluidineHCID 23668193Sodium Nitrite

生成物 1

HCID 805030315-Bromo-2-methylbenzenediazonium tetrafluoroborate

試薬・触媒・溶媒 1

HCID 962Water溶媒2 回

実験手順

Sodium nitrite (0.56 g) in water(2.0 mL) was slowly added to a mixture of 2-methyl-5-bromoaniline (1.50 g) in tetrafluoroboric acid (6.0 mL) and water (4.0 mL) at 0-5° C. After addition, the reaction was stirred at room temperature for 30 min. The mixture was cooled to 0° C., filtered, washed with cold water, cold methanol and ether. The mixture was then dried to provide the product 5-bromo-2-methylphenyldiazonium tetrafluroborate (1.90 g).

後処理

  1. additionAfter addition
  2. temperatureThe mixture was cooled to 0° C.
  3. filtrationfiltered
  4. washwashed with cold water, cold methanol and ether
  5. customThe mixture was then dried

出典と根拠

ORDレコード
ord-c40fbaf2bc8a4252b5efdb5020ba1033
出典データセット
uspto-grants-2014_01
特許番号
US08637497B2

関連ノート

読み込み中…