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Atrolactic acid, (-)- → [(7R)-7-{[(2R)-2-hydroxy-2-phenylpropanoyl](methyl)amino}-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Atrolactic acid, (-)- | HCID 736858 | — |
| 反応物 | propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate | HCID 86655417 | — |
| 生成物 | [(7R)-7-{[(2R)-2-hydroxy-2-phenylpropanoyl](methyl)amino}-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetic acid | HCID 58349686 | — |
反応手順
The title compound was prepared using analogous procedures described in Example 1 (Method A) from (2R)-2-hydroxy-2-phenylpropanoic acid and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 407.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08637671B2 |
| 出典データセット | uspto-grants-2014_01 |
| ORD ID | ord-c547cb46b5a84a1c81572e02402447db |
| 出典メモ | uspto-grants-2014_01 |