Ethanol → 5-Ethoxy-1,5-dihydro-2H-pyrrol-2-one

HRID 476636ノート

反応式

HRID 476636 の反応式
[OH:1][CH:2]1[NH:6][C:5](=[O:7])[CH:4]=[CH:3]1.[CH2:8](O)[CH3:9]>>[CH2:8]([O:1][CH:2]1[NH:6][C:5](=[O:7])[CH:4]=[CH:3]1)[CH3:9]

参加物

3

反応物 2

HCID 702EthanolHCID 353549(R)-Dihydromaleimide

生成物 1

HCID 133284325-Ethoxy-1,5-dihydro-2H-pyrrol-2-one

実験手順

A mixture of 2.3 g of 1,5-dihydro-5-hydroxy-2H-pyrrol-2-one in 140 cm3 of ethanol and 100 g of Amberlite resin IR-120 (H) is taken to reflux for 30 minutes. After allowing to cool, filtering off the resin and distilling the ethanol off under reduced pressure, 2.76 g of the expected product is obtained, m.p. 50°-52° C.

後処理

  1. temperatureto reflux for 30 minutes
  2. temperatureto cool
  3. filtrationfiltering off the resin
  4. distillationdistilling the ethanol off under reduced pressure

出典と根拠

ORDレコード
ord-b86384fcb80b44178ebb443b4e54f4b1
出典データセット
uspto-grants-1989_12
特許番号
US04885307

反応ノート

読み込み中…