Propionyl chloride → HCID 19838438、化合物
反応式
[C:1](Cl)(=[O:4])[CH2:2][CH3:3].Cl.[NH2:7][CH:8]1[CH2:20][C:19]2[C:11](=[CH:12][C:13]3[CH2:17][CH2:16][O:15][C:14]=3[CH:18]=2)[CH2:10][CH2:9]1>C1C=CC=CC=1.C(N(CC)CC)C.O>[C:1]([NH:7][CH:8]1[CH2:20][C:19]2[C:11](=[CH:12][C:13]3[CH2:17][CH2:16][O:15][C:14]=3[CH:18]=2)[CH2:10][CH2:9]1)(=[O:4])[CH2:2][CH3:3]参加物
6
実験手順
A solution of propionyl chloride in 50 ml of benzene is added dropwise to a solution of 5 g of the compound of Example 2 in 100 ml of benzene and 4.2 ml of triethylamine. After one and a half hours' refluxing, the cooled mixture is diluted with water, separated off after being left to settle and extracted with benzene, and the organic phase is washed with water, dried over anhydrous sodium sulfate and evaporated under vacuum. The dry residue is recrystallized in acetonitrile.