Benzylamine → Benzeneacetamide, 4-hydroxy-N-(phenylmethyl)-

HRID 476853ノート

反応式

HRID 476853 の反応式
CO[C:3](=[O:12])[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([OH:11])=[CH:7][CH:6]=1.[CH2:13]([NH2:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH2:13]([NH:20][C:3](=[O:12])[CH2:4][C:5]1[CH:6]=[CH:7][C:8]([OH:11])=[CH:9][CH:10]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

参加物

3

反応物 2

HCID 7504BenzylamineHCID 518900Benzeneacetic acid, 4-hydroxy-, methyl ester

生成物 1

HCID 8376026Benzeneacetamide, 4-hydroxy-N-(phenylmethyl)-

実験手順

A mixture of 80 g of 4-hydroxyphenylacetic acid methyl ester and 51.6 g of benzylamine is brought to 180° C. for 8 hours. The mixture is allowed to return to room temperature and the crystals are filtered off and washed with ethanol and then ethyl ether.

後処理

  1. customto return to room temperature
  2. filtrationthe crystals are filtered off
  3. washwashed with ethanol

出典と根拠

ORDレコード
ord-467e9f33b6914da9b3e0388437aff99c
出典データセット
uspto-grants-1989_12
特許番号
US04886799

反応ノート

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