Methyl 2-(4-(2-oxopropyl)phenoxy)acetate → N-[2-(4-Carbomethoxymethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(thiazol-4-yl)ethanamine
反応式
[OH:1][CH:2]([C:5]1[N:6]=[CH:7][S:8][CH:9]=1)[CH2:3][NH2:4].[C:10]([CH2:14][O:15][C:16]1[CH:21]=[CH:20][C:19]([CH2:22][C:23](=O)[CH3:24])=[CH:18][CH:17]=1)([O:12][CH3:13])=[O:11]>>[C:10]([CH2:14][O:15][C:16]1[CH:17]=[CH:18][C:19]([CH2:22][CH:23]([NH:4][CH2:3][CH:2]([OH:1])[C:5]2[N:6]=[CH:7][S:8][CH:9]=2)[CH3:24])=[CH:20][CH:21]=1)([O:12][CH3:13])=[O:11]参加物
3
実験手順
Prepared analogously to Example 13 by reaction of 2-hydroxy-2-(thiazol-4-yl)ethylamine with 1-(4-carbomethoxymethoxyphenyl)propan-2-one followed by purification of the base on a silica gel column using ethyl acetate/methanol=8:2 as eluant.
後処理
- customfollowed by purification of the base on a silica gel column
出典と根拠
- ORDレコード
- ord-ff23ba13469049b3a1483430318ab2bd
- 出典データセット