化工社化工社 化学情報印刷レポート · 研究参考用
Sodium ethoxide → Diethyl 5-allylthio-2-dimethylamino-2,4-hexadienedioate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium ethoxide | HCID 2723922 | — |
| 反応物 | Ethyl [(prop-2-en-1-yl)sulfanyl]acetate | HCID 12717294 | — |
| 反応物 | N-(dimethylamino-3-ethoxycarbonylpropenylidene)-N-methylmethanaminium tetrafluoroborate | HCID 86743575 | — |
| 反応物 | Diethyl 2-dimethylamino-5-phenylthio-2,4-hexadienedioate | HCID 86743580 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Diethyl 5-allylthio-2-dimethylamino-2,4-hexadienedioate | HCID 54345555 | 84.6% |
反応手順
The procedure is as in Example 2 for the preparation of diethyl 2-dimethylamino-5-phenylthio-2,4-hexadienedioate, starting with N-(3-dimethylamino-3-ethoxycarbonylpropenylidene)-N-methylmethanaminium tetrafluoroborate (5.5 g), a 2M ethanolic solution of sodium ethylate (9.7 cc) and ethyl (allylthio)acetate (3.1 g) in ethanol (31 cc). Diethyl 5-allylthio-2-dimethylamino-2,4-hexadienedioate (5.1 g) is thereby obtained, and is used in the crude state in the subsequent phases.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04886835 |
| 出典データセット | uspto-grants-1989_12 |
| ORD ID | ord-521fc0e724324f72989f88da60a68ab7 |
| 出典メモ | uspto-grants-1989_12 |