2-Chloro-3',4'-dihydroxyacetophenone → 3',4'-Dihydroxy-2-(methylthio)acetophenone
反応式
CC[C:3](C1C=CC=CC=1)=[S:4].Cl[CH2:12][C:13]([C:15]1[CH:16]=[C:17]([OH:22])[C:18](=[CH:20][CH:21]=1)[OH:19])=[O:14].C[S-].[Na+]>CO>[CH3:3][S:4][CH2:12][C:13]([C:15]1[CH:16]=[C:17]([OH:22])[C:18](=[CH:20][CH:21]=1)[OH:19])=[O:14]参加物
5
実験手順
The procedure is as in Example 4 for the preparation of α-methylthioacetophenone, starting with a stirred solution of 4-(2-chloroacetyl)pyrocatechol (18.6 g) in methanol (200 cc). Sodium methanethiolate (7 g) is added in the course of 15 minutes at a temperature in the region of 20° C., and the mixture is left with stirring for 3 hours at the same temperature. 4-[2-(Methylthio)acetyl]pyrocatechol (14.5 g), m.p. 107° C., is thereby obtained.
後処理
- waitthe mixture is left
出典と根拠
- ORDレコード
- ord-c187bcbca0a64fd1885eae865d8b0418
- 出典データセット
- uspto-grants-1989_12
- 特許番号
- US04886835
反応ノート
読み込み中…