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Ethyl Thioglycolate → Ethyl (3-phenoxybenzylthio)acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl Thioglycolate | HCID 12185 | — |
| 反応物 | 1-(Chloromethyl)-4-phenoxybenzene | HCID 520994 | — |
| 反応物 | Sodium ethoxide | HCID 2723922 | — |
| 反応物 | Ethyl (4-methylbenzylthio)acetate | HCID 4107274 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Ethyl (3-phenoxybenzylthio)acetate | HCID 53984256 | — |
反応手順
The procedure is as in Example 29 for the preparation of ethyl (4-methylbenzylthio)acetate, starting with 1-chloromethyl-4-phenoxybenzene (21.5 g), a 2M ethanolic solution of sodium ethylate (50 cc) and ethyl 2-mercaptoacetate (12.2 g) in ethanol (200 cc). Ethyl (3-phenoxybenzylthio)acetate (28.8 g) is thereby obtained, and is used in the crude state in the subsequent syntheses.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04886835 |
| 出典データセット | uspto-grants-1989_12 |
| ORD ID | ord-133d19a2715a462a97cf308f0d226e38 |
| 出典メモ | uspto-grants-1989_12 |