化工社化工社 化学情報印刷レポート · 研究参考用
Sodium ethoxide → Diethyl 2-dimethylamino-5-(4-trifluoromethylbenzylthio)-2,4-hexadienedioate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium ethoxide | HCID 2723922 | — |
| 反応物 | Ethyl (4-trifluoromethylbenzylthio)acetate | HCID 54499618 | — |
| 反応物 | N-(dimethylamino-3-ethoxycarbonylpropenylidene)-N-methylmethanaminium tetrafluoroborate | HCID 86743575 | — |
| 反応物 | Diethyl 2-dimethylamino-5-phenylthio-2,4-hexadienedioate | HCID 86743580 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Diethyl 2-dimethylamino-5-(4-trifluoromethylbenzylthio)-2,4-hexadienedioate | HCID 54091184 | 84.9% |
反応手順
The procedure is as in Example 2, for the preparation of diethyl 2-dimethylamino-5-phenylthio-2,4-hexadienedioate, starting with N-(3-dimethylamino-3-ethoxycarbonylpropenylidene)-N-methylmethanaminium tetrafluoroborate (5.7 g), a 2M ethanolic solution of sodium ethylate (50 cc) and ethyl (4-trifluoromethylbenzylthio)acetate (5.6 g) in ethanol (50 cc). Diethyl 2-dimethylamino-5-(4-trifluoromethylbenzylthio)-2,4-hexadienedioate (7.3 g) is thereby obtained in the form of a yellow oil, and is used in the crude state in the subsequent syntheses.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04886835 |
| 出典データセット | uspto-grants-1989_12 |
| ORD ID | ord-212179cb33d84cb3a424bbb2582ad213 |
| 出典メモ | uspto-grants-1989_12 |