化工社化工社 化学情報印刷レポート · 研究参考用
Benzyl Chloride → 5-(benzylsulfanyl)-4H-1,2,4-triazol-3-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl Chloride | HCID 7503 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | 5-amino-1H-1,2,4-triazole-3-thiol | HCID 178509296 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 5-(benzylsulfanyl)-4H-1,2,4-triazol-3-amine | HCID 737272 | 90.6% |
反応手順
3-Amino-5-mercapto-1,2,4-triazole (40.36 g) was treated at room temperature with sodium hydroxide (13.9 g) in ethanol (450 ml), and benzyl chloride (44.3 g) was added. The mixture was stirred overnight, and was then filtered. The ethanol was evaporated off, and the residue was recrystallised from ethyl acetate to give 64.97 g of the desired product, mp 104° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04889553 |
| 出典データセット | uspto-grants-1989_12 |
| ORD ID | ord-b82cfc36a6374223bdd0d890c06b2c86 |
| 出典メモ | uspto-grants-1989_12 |