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Cyproheptadine → 2-[(4-Methylpiperazin-1-yl)methyl]morpholine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cyproheptadine | HCID 2913 | — |
| 反応物 | 1-Methylpiperazine | HCID 53167 | — |
| 反応物 | 4-Benzyl-2-(chloromethyl)morpholine | HCID 2801562 | — |
| 生成物 | 2-[(4-Methylpiperazin-1-yl)methyl]morpholine | HCID 14627568 | — |
反応手順
By the use of 2-chloromethyl-4-benzylmorpholine and N-methylpiperazine, the reactin is similarly carried out as Reference example 2 to give 2-(4-methyl-1-piperazinylmethyl) morpholine.trihydrochloride as white crystals, melting at 210°-212° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04889857 |
| 出典データセット | uspto-grants-1989_12 |
| ORD ID | ord-169f0a72445b4186ab52fd476f25a5a6 |
| 出典メモ | uspto-grants-1989_12 |