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HRID 477841作成日：2026年10月26日

1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → 1-Cyclopropyl-7-[2-(dimethylaminomethyl)morpholino]-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid

https://huagongshe.com/reaction/477841

反応式

関与物質

役割名称HCID仕込み量
反応物1-Cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acidHCID 535414—
反応物Dimethyl-morpholin-2-ylmethyl-amineHCID 3401489—
生成物1-Cyclopropyl-7-[2-(dimethylaminomethyl)morpholino]-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acidHCID 10454056—

反応手順

By the use of 1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid and 2-(dimethylaminomethyl)morpholine, the reaction is similarly carried out as Example 1 to give 1-cyclopropyl-7-[2-(dimethylaminomethyl)morpholino]-6,8-difluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, melting at 182°-183° C.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US04889857
出典データセットuspto-grants-1989_12
ORD IDord-a59dfd2d09974ac0be9401af878d1de9
出典メモuspto-grants-1989_12