Acetic Acid → (1,1'-Bi(cyclohexane))-4-carboxylic acid

HRID 477962

反応式

HRID 477962 の反応式
[C:1]1([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH:6]=[CH:5][C:4]([C:7]([OH:9])=[O:8])=[CH:3][CH:2]=1.C(O)(=O)C>C(O)C.[Pt]=O>[CH:1]1([CH:10]2[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]2)[CH2:2][CH2:3][CH:4]([C:7]([OH:9])=[O:8])[CH2:5][CH2:6]1

参加物

5

反応物 2

HCID 176Acetic AcidHCID 66724(1,1'-Biphenyl)-4-carboxylic acid

生成物 1

HCID 3062287(1,1'-Bi(cyclohexane))-4-carboxylic acid収率 99.9%

試薬・触媒・溶媒 2

HCID 82844Platinum oxide (PtO)触媒HCID 702Ethanol溶媒

実験手順

A solution of biphenyl-4-carboxylic acid (9.9 g, 50 mmol) in 500 ml of ethanol and 150 ml of glacial acetic acid containing 1.0 g of platinum oxide was hydrogenated overnight at 40 psi. Upon filtering the solution and concentrating the filtrate under reduced pressure, 10.5 g of bicyclohexyl-4-carboxylic acid was obtained as a white solid (m.p. 122°-125° C.).

後処理

  1. filtrationUpon filtering the solution
  2. concentrationconcentrating the filtrate under reduced pressure

出典と根拠

ORDレコード
ord-5c7754857a03410781bccfdb46480e02
出典データセット
uspto-grants-1989_12
特許番号
US04889874

関連ノート

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