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Batyl Alcohol → 1-O-Octadecyl-3-O-[2-[2-(2-trityloxyethoxy)ethoxy]ethyl]glycerol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Batyl Alcohol | HCID 3681 | — |
| 反応物 | Trityl chloride | HCID 6456 | — |
| 反応物 | Triethylene Glycol | HCID 8172 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | Sodium 4-methylbenzenesulfonate | HCID 3720192 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 1-O-Octadecyl-3-O-[2-[2-(2-trityloxyethoxy)ethoxy]ethyl]glycerol | HCID 14877714 | 42.2% |
反応手順
10.3 g (30 millimole) of batyl alcohol, 6.1 g (32 millimole) of sodium p-toluenesulfonate, 50 ml of pyridine, 1.6 g (40 millimole) of 60% oily sodium hydride, 45 g (300 millimole) of triethylene glycol, and 8.4 g (30 millimole) of trityl chloride were treated by following a procedure similar to that of Working Example 1, to give 9.1 g (42%) of the above-captioned compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04889953 |
| 出典データセット | uspto-grants-1989_12 |
| ORD ID | ord-86ee1e5ae9874216bdc3b8f1993af70d |
| 出典メモ | uspto-grants-1989_12 |