Benzeneacetic acid, 4-bromo- → 2-[(4-Bromophenyl)acetamido]butyric acid isobutyl ester

HRID 478799

反応式

HRID 478799 の反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([OH:11])=O)=[CH:4][CH:3]=1.[NH2:12][CH:13]([CH2:21][CH3:22])[C:14]([O:16][CH2:17][CH:18]([CH3:20])[CH3:19])=[O:15]>>[CH2:17]([O:16][C:14](=[O:15])[CH:13]([NH:12][C:9](=[O:11])[CH2:8][C:5]1[CH:4]=[CH:3][C:2]([Br:1])=[CH:7][CH:6]=1)[CH2:21][CH3:22])[CH:18]([CH3:19])[CH3:20]

参加物

3

反応物 2

HCID 74654Benzeneacetic acid, 4-bromo-HCID 13743360Isobutyl 2-aminobutyrate

生成物 1

HCID 155476402-[(4-Bromophenyl)acetamido]butyric acid isobutyl ester

実験手順

Following General Procedure I above and using 4-bromophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure. NMR data was as follows:

後処理

  1. customThe reaction was monitored by tlc on silica gel and purification
  2. filtrationwas by filtration

出典と根拠

ORDレコード
ord-63a40501a11644d991fec9022439a6ad
出典データセット
uspto-grants-2003_11
特許番号
US06642261B2

関連ノート

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