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HRID 478802作成日:2026年10月26日

Benzeneacetic acid, 2-fluoro- → 2-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl Ester

https://huagongshe.com/reaction/478802

反応式

関与物質

役割名称HCID仕込み量
反応物Benzeneacetic acid, 2-fluoro-HCID 67979—
反応物Isobutyl 2-aminobutyrateHCID 13743360—
生成物2-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl EsterHCID 53643249—

反応手順

Following General Procedure I above and using 2-fluorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was By filtration as described in the general procedure. NMR data was as follows:

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US06642261B2
出典データセットuspto-grants-2003_11
ORD IDord-68c4b4157d714eb5aed1f4de634e96ff
出典メモuspto-grants-2003_11