Ammonia → 8-Hydroxy-2-methyl-7-quinolinecarboxamide

HRID 4789

反応式

HRID 4789 の反応式
C[O:2][C:3]([C:5]1[C:14]([OH:15])=[C:13]2[C:8]([CH:9]=[CH:10][C:11]([CH3:16])=[N:12]2)=[CH:7][CH:6]=1)=O.[NH3:17]>>[OH:15][C:14]1[C:5]([C:3]([NH2:17])=[O:2])=[CH:6][CH:7]=[C:8]2[C:13]=1[N:12]=[C:11]([CH3:16])[CH:10]=[CH:9]2

参加物

3

反応物 2

HCID 222Ammonia2 回HCID 545112118-Hydroxy-2-methyl-7-quinolinecarboxylic acid methyl ester

生成物 1

HCID 212714728-Hydroxy-2-methyl-7-quinolinecarboxamide

実験手順

8-Hydroxy-2-methyl-7-quinolinecarboxylic acid methyl ester is reacted with excess ammonia in a steel bomb for 12-18 hr. The excess ammonia is allowed to evaporate and the residue is crystallized from a suitable solvent to give the title compound.

後処理

  1. customto evaporate
  2. customthe residue is crystallized from a suitable solvent

出典と根拠

ORDレコード
ord-abab3f08dfb7407e8adcdfc18a9a3ffd
出典データセット
uspto-grants-1988_02
特許番号
US04727152

関連ノート

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