Hydrochloric Acid → 2-Benzylamino-5-nitropyridine
反応式
Cl[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][N:3]=1.[CH2:11]([NH2:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.Cl>C(O)C>[CH2:11]([NH:18][C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][N:3]=1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1参加物
5
実験手順
A solution of 2-chloro-5-nitropyridine (1.59 g, 10 mmol) and benzylamine (2.3 mL, 21 mmol) in ethanol (10 mL) was heated at reflux for 2 h. The reaction mixture was allowed to ambient temperature, 1.2 N HCl was added, the precipitate collected, rinsed with water, and dried to give 2.02 g of 2-benzylamino-5-nitropyridine as a yellow solid.
後処理
- temperatureat reflux for 2 h
- customwas allowed to ambient temperature
- customthe precipitate collected
- washrinsed with water
- customdried
出典と根拠
- ORDレコード
- ord-e3b89971557d4186856e732d6ddf069d
- 出典データセット
- uspto-grants-2003_11
- 特許番号
- US06646124B2
反応ノート
読み込み中…