化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → Ethyl 6-chloropicolinate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | 6-Chloropicolinic acid | HCID 20812 | — |
| 生成物 | Ethyl 6-chloropicolinate | HCID 11063114 | — |
反応手順
14.1 g (0.0895 mole) of 2-chloro-6-hydroxycarbonylpyridine in 133 ml of a solution of HCl in ethanol is heated for 8 hours under reflux. The solvent is evaporated off, ethyl acetate added and the mixture washed with a solution of bicarbonate. The solvent is further evaporated and the reaction product purified by flash chromatography (cyclohexane/ethyl acetate=7/3). The required product is obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06649627B1 |
| 出典データセット | uspto-grants-2003_11 |
| ORD ID | ord-862cce06f01145b7962a2921dbe2c91c |
| 出典メモ | uspto-grants-2003_11 |