Propylamine → HCID 178457658、化合物
反応式
OC([C:30]1[CH:31]=[C:32]2[C:37](=[CH:38][CH:39]=1)[CH:36]=[C:35]([C:40]([O:42]C)=O)[CH:34]=[CH:33]2)(C1N=CN(C(C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)C=1)C(C)C.[OH:44][C:45](C1C=C2C(=CC=1)C=C(C(O)=O)C=C2)([C:49]1[N:50]=[CH:51][N:52](C(C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[CH:53]=1)[CH:46]([CH3:48])[CH3:47].[CH2:86]([NH2:89])[CH2:87][CH3:88]>>[OH:44][C:45]([C:36]1[C:37]2[C:32](=[CH:31][CH:30]=[CH:39][CH:38]=2)[CH:33]=[CH:34][C:35]=1[C:40]([NH:89][CH2:86][CH2:87][CH3:88])=[O:42])([C:49]1[N:50]=[CH:51][NH:52][CH:53]=1)[CH:46]([CH3:48])[CH3:47]参加物
4
実験手順
In a manner to that described in Example 9-(i), methyl 6-(1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl)-2-naphthoate (2.83 g) was converted to 6-(1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl)-2-naphthoic acid, which was reacted with n-propylamine (0.66 mL) in a similar manner as described in Example 24-(i) to give the titled compound (2.74 g) as a colorless powder.