Benzeneacetic acid, 2-fluoro- → 2-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl Ester

HRID 480895

反応式

HRID 480895 の反応式
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=O.[NH2:12][CH:13]([CH2:21][CH3:22])[C:14]([O:16][CH2:17][CH:18]([CH3:20])[CH3:19])=[O:15]>>[CH2:17]([O:16][C:14](=[O:15])[CH:13]([NH:12][C:9](=[O:11])[CH2:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[F:1])[CH2:21][CH3:22])[CH:18]([CH3:19])[CH3:20]

参加物

3

反応物 2

HCID 67979Benzeneacetic acid, 2-fluoro-HCID 13743360Isobutyl 2-aminobutyrate

生成物 1

HCID 536432492-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl Ester

実験手順

Following General Procedure BI above and using 2-fluorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

後処理

  1. customThe reaction was monitored by tlc on silica gel and purification
  2. filtrationwas by filtration

出典と根拠

ORDレコード
ord-38733695a08a4aa69a7329b0114245bb
出典データセット
uspto-grants-2003_11
特許番号
US06653303B1

関連ノート

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