化工社化工社 化学情報印刷レポート · 研究参考用
Benzyl Bromide → 2-(Benzyloxy)-6-bromonaphthalene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl Bromide | HCID 7498 | — |
| 反応物 | 6-Bromo-2-naphthalenol | HCID 27144 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 溶媒 | Cesium carbonate | HCID 10796 | — |
| 生成物 | 2-(Benzyloxy)-6-bromonaphthalene | HCID 640595 | — |
反応手順
To the commercially available 6-bromo-naphthalene-2-ol (1) (1 equi.) and benzyl bromide (2) (1 equi.) in DMF (3mL/mmole), cesium carbonate (1.25 equi.) was added at room temperature. The reaction mixture was stirred at that temperature for 24 h, quenched with water, extracted with ethyl acetate:hexane (1:1), washed with brine, over MgSO4, and concentrated in vacuo.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06703082B1 |
| 出典データセット | uspto-grants-2004_03 |
| ORD ID | ord-2d89c4a6c19742cea11d66a9ead29487 |
| 出典メモ | uspto-grants-2004_03 |