化工社化工社 化学情報印刷レポート · 研究参考用
1-(1-Naphthyl)piperazine → 2-Chloro-1-[4-(1-naphthyl)piperazin-1-yl]ethanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(1-Naphthyl)piperazine | HCID 1342 | — |
| 反応物 | Chloroacetyl chloride | HCID 6577 | — |
| 反応物 | Calcium Carbonate | HCID 10112 | — |
| 反応物 | 2-Chloro-1-(4-o-tolylpiperazin-1-yl)ethanone | HCID 4741212 | — |
| 溶媒 | Methyl Ethyl Ketone | HCID 6569 | — |
| 生成物 | 2-Chloro-1-[4-(1-naphthyl)piperazin-1-yl]ethanone | HCID 4741241 | 92% |
反応手順
Compound 49A is prepared according to the procedure described for compound 12A using the following reactants: chloroacetyl chloride (270 ml, 3.45 mmol); 1-(1-naphthyl)piperazine (610 mg, 2.88 mmol); calcium carbonate (860 mg, 8.64 mmol); methyl ethyl ketone (20 ml).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05789412 |
| 出典データセット | uspto-grants-1998_08 |
| ORD ID | ord-9322168791ba41ad9e780d551849caaa |
| 出典メモ | uspto-grants-1998_08 |