(2S,3S)-tert-Butyl 3-amino-2-phenylpiperidine-1-carboxylate → (2S,3S)-1-tert-Butoxycarbonyl-3-(5-cyanomethyl-2-methoxybenzyl)amino-2-phenylpiperidine

反応式

N[C@H]1CCCN(C(OC(C)(C)C)=O)[C@H]1C1C=CC=CC=1.[C:21]([O:25][C:26]([N:28]1[CH2:33][CH2:32][CH2:31][C@H:30]([NH:34][CH2:35][C:36]2[CH:41]=[C:40]([CH:42]([C:44]#[N:45])C)[CH:39]=[CH:38][C:37]=2[O:46][CH3:47])[C@@H:29]1[C:48]1[CH:53]=[CH:52][CH:51]=[CH:50][CH:49]=1)=[O:27])([CH3:24])([CH3:23])[CH3:22]>>[C:21]([O:25][C:26]([N:28]1[CH2:33][CH2:32][CH2:31][C@H:30]([NH:34][CH2:35][C:36]2[CH:41]=[C:40]([CH2:42][C:44]#[N:45])[CH:39]=[CH:38][C:37]=2[O:46][CH3:47])[C@@H:29]1[C:48]1[CH:49]=[CH:50][CH:51]=[CH:52][CH:53]=1)=[O:27])([CH3:24])([CH3:22])[CH3:23]