化工社化工社 化学情報印刷レポート · 研究参考用
2-(4-Methoxyphenyl)-4-(2-nitrophenyl)imidazole → HCID 178488922、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(4-Methoxyphenyl)-4-(2-nitrophenyl)imidazole | HCID 178488923 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | HCID 178488922 | HCID 178488922 | 102.4% |
反応手順
2-(4-Methoxyphenyl)-4-(2-nitrophenyl)imidazole (10 g) is mixed with EtOH (80 ml) and 5% Pd-C (wet, 2 g). The mixture is shaken under hydrogen at 50 psi for 45 min. then filtered through Celite. The filtrate is evaporated under reduced pressure to yield 2-(4-methoxyphenyl)-4-(2-aminophenyl)imidazole (9.2 g) as a brown solid which is used in the next step without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05792766 |
| 出典データセット | uspto-grants-1998_08 |
| ORD ID | ord-98cf92f716584d32a3b44bbdbb725d0f |
| 出典メモ | uspto-grants-1998_08 |