Sulfuric Acid → 1,2,3,4-Tetrahydroquinoline-5,6-diamine
反応式
[N:1]1[C:10]2[C:5](=[C:6]([NH2:12])[C:7]([NH2:11])=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.S(=O)(=O)(O)O>CO.[Pt]=O>[NH2:12][C:6]1[C:7]([NH2:11])=[CH:8][CH:9]=[C:10]2[C:5]=1[CH2:4][CH2:3][CH2:2][NH:1]2参加物
5
実験手順
A solution of 5,6-quinolinediamine (12.5 g, 0.065 mol) and sulfuric acid (8 mL) in methanol (250 mL) was treated with platinum oxide (1 g) in a Parr apparatus under hydrogen for 16 hours. An additional 1 g portion of platinum oxide was added and hydrogenation continued for 44 hours additional. Standard work-up gave the 5,6-diaminotetrahydroquinoline.
出典と根拠
- ORDレコード
- ord-71bc07ae0cd34c7fa0e0d08e19635dce
- 出典データセット
- uspto-grants-2004_03
- 特許番号
- US06703391B2
反応ノート
読み込み中…