1-Butanol → 1,1-Dibutoxycyclohexane

HRID 482141

反応式

HRID 482141 の反応式
[C:1]1(=[O:7])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:8]([OH:12])[CH2:9][CH2:10][CH3:11]>O.O.O.O.O.O.[Cl-].[Ce+3].[Cl-].[Cl-].C1(C)C=CC=CC=1>[CH2:6]([O:7][C:1]1([O:12][CH2:8][CH2:9][CH2:10][CH3:11])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1)[CH2:1][CH2:2][CH3:3]

参加物

5

反応物 2

HCID 2631-ButanolHCID 7967Cyclohexanone

生成物 1

HCID 2437181,1-Dibutoxycyclohexane収率 185.8%

試薬・触媒・溶媒 2

HCID 22347666cerium(III) chloride hexahydrate触媒HCID 1140Toluene溶媒

反応条件

温度
25 °C

実験手順

In a 300-ml three-necked flask, 98 g (1 mole) of cyclohexanone, 148 g (2 moles) of n-butanol, 50 g of molecular sieve 4A, 2 mg of cerium chloride hexahydrate and 40 g of toluene were charged. The resulting mixture was stirred at 25° C. under atmospheric pressure for 12 hours in a nitrogen atmosphere. After the removal of the molecular sieve 4A, the solvent (toluene) and unreacted starting materials were distilled off under reduced pressure. Distillation of the residue under reduced pressure gave 212.2 g of cyclohexanone dibutyl acetal (yield: 93.1%).

後処理

  1. customAfter the removal of the molecular sieve 4A
  2. distillationwere distilled off under reduced pressure
  3. distillationDistillation of the residue under reduced pressure

出典と根拠

ORDレコード
ord-dae1db1790a9481699e48cfae4a326c1
出典データセット
uspto-grants-1998_08
特許番号
US05792876

関連ノート

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