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Calcium Carbonate → gamma-chloropropyl N-(5-chloro-4-hydroxy-2-nitrophenyl)-carbamate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Calcium Carbonate | HCID 10112 | — |
| 反応物 | Carbonochloridic acid, 3-chloropropyl ester | HCID 69399 | — |
| 反応物 | 4-Amino-2-chloro-5-nitrophenol | HCID 18950617 | — |
| 溶媒 | 1,2-Dimethoxyethane | HCID 8071 | — |
| 生成物 | gamma-chloropropyl N-(5-chloro-4-hydroxy-2-nitrophenyl)-carbamate | HCID 20244610 | — |
反応手順
37.7 g (0.2 mole) of 6-chloro-3-nitro-4-aminophenol are dissolved in 120 ml of dimethoxyethane, 11 g of calcium carbonate are added and 32 g of γ-chloropropyl chloroformate are added dropwise at 70° C. After 1 hour at 90° C., the mixture is filtered hot and the filtrate is stirred into 300 ml of ice-water. The initially oily product crystallises after a short time.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04575378 |
| 出典データセット | uspto-grants-1986_03 |
| ORD ID | ord-d7662345536f47cfb421a57164b00f62 |
| 出典メモ | uspto-grants-1986_03 |