2-Methylbenzenesulfonic acid → HCID 13644521、化合物
反応式
O[CH:2]1[C:11]2[C:6](=[CH:7][C:8]([F:12])=[CH:9][CH:10]=2)[C:5]2([C:16](=[O:17])[NH:15][C:14](=[O:18])[NH:13]2)[CH2:4][CH2:3]1.C1(C)C(S(O)(=O)=O)=CC=CC=1>C1(C)C=CC=CC=1>[F:12][C:8]1[CH:7]=[C:6]2[C:11]([CH:2]=[CH:3][CH2:4][C:5]32[C:16](=[O:17])[NH:15][C:14](=[O:18])[NH:13]3)=[CH:10][CH:9]=1参加物
4
実験手順
3',4',-Dihydro-4'-hydroxy-7'-fluorospiro[imidazolidine-4,1'(2'H)-naphthalene]2,5-dione (3.2 g., 0.013 mole) was added to 75 ml. of toluene containing a trace of -toluenesulfonic acid and the mixture heated to reflux for 5 hours. The toluene was removed in vacuo and the residue triturated with diethyl ether and filtered, 2.6 g. (87% yield).
後処理
- temperatureto reflux for 5 hours
- customThe toluene was removed in vacuo
- customthe residue triturated with diethyl ether
- filtrationfiltered
出典と根拠
- ORDレコード
- ord-1f8ff5667a1c4f4c83ce958f46f003e5
- 出典データセット
- uspto-grants-1986_03
- 特許番号
- US04575507
反応ノート
読み込み中…