Dichloromethane → 2-Chloro-2-(methylsulfanyl)pent-4-enenitrile

HRID 482823ノート

反応式

HRID 482823 の反応式
[CH3:1][S:2][CH:3]([CH2:6][CH:7]=[CH2:8])[C:4]#[N:5].C(Cl)[Cl:10]>>[Cl:10][C:3]([S:2][CH3:1])([CH2:6][CH:7]=[CH2:8])[C:4]#[N:5]

参加物

3

反応物 2

HCID 6344Dichloromethane2 回HCID 138132372-Methylthio-4-pentenenitrile

生成物 1

HCID 138132392-Chloro-2-(methylsulfanyl)pent-4-enenitrile

実験手順

2×10-2 moles of 2-methylthio-4-pentenenitrile are then dissolved in 50 ml of dry CH2Cl2. 2×10-2 moles of SO2Cl2 dissolved in 10 ml of CH2Cl2 are added dropwise. The mixture is stirred until gas evolution has ceased (silicone oil trap). The solvent is evaporated off and distillation is carried out at 82° C. at a pressure of 12 mm of mercury. 2-Chloro-2-methylthio-4-pentene-nitrile is obtained in a yield of over 95%.

後処理

  1. additionare added dropwise
  2. customThe solvent is evaporated off
  3. distillationdistillation
  4. customis carried out at 82° C. at a pressure of 12 mm of mercury

出典と根拠

ORDレコード
ord-1d29117cfcb046b5943ab8d33f8dd82c
出典データセット
uspto-grants-1986_03
特許番号
US04576759

反応ノート

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