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HRID 482970作成日:2026年10月26日

Thiamine Hydrochloride → thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-, salt with 1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-2-naphthalenesulfonic acid (1:1), mono(1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-2-naphthalenesulfonate) (salt)

https://huagongshe.com/reaction/482970

反応式

関与物質

役割名称HCID仕込み量
反応物Thiamine HydrochlorideHCID 6202—
反応物Menadione Sodium BisulfiteHCID 23665888—
溶媒WaterHCID 962—
生成物thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-, salt with 1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-2-naphthalenesulfonic acid (1:1), mono(1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-2-naphthalenesulfonate) (salt)HCID 121232542—

反応手順

25 g of thiamine hydrochloride (vitamin B1) was dissolved in 50 g of water; to said solution of 25 g of powdery sodium menadione bisulfite was added within about half an hour. After half an hour of agitation, the reaction mass became opalescent and the adduct began to precipitate. After an hour, the precipitate was filtered, washed and dried. 25 g of a white product having the following analysis was obtained.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US04577019
出典データセットuspto-grants-1986_03
ORD IDord-a76a9e7bad3d40479e682b9c4056a987
出典メモuspto-grants-1986_03