HCID 178487721、化合物 → HCID 178487715、化合物

HRID 48302

反応式

HRID 48302 の反応式
[OH:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]([O:12][CH3:13])=[CH:9][CH:10]=2)[N:5]=[CH:4][C:3]=1C(O)=O>C1C=CC(C2C=CC=CC=2)=CC=1.C1C=CC(OC2C=CC=CC=2)=CC=1>[CH3:13][O:12][C:8]1[CH:7]=[C:6]2[C:11]([C:2]([OH:1])=[CH:3][CH:4]=[N:5]2)=[CH:10][CH:9]=1

参加物

3

反応物 1

HCID 178487721HCID 178487721、化合物

生成物 1

HCID 178487715HCID 178487715、化合物収率 97%

試薬・触媒・溶媒 1

HCID 246701,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene)溶媒

実験手順

A suspension of 4-hydroxy-7-methoxyquinoline-3-carboxylic acid (4.0 g) in Dowtherm A (75 mL) was heated at reflux for 2 hrs. The resulting brown solution was allowed to slowly cool to ambient temperature. The resulting precipitate was isolated by filtration and then dried in a vacuum oven at 80° C. for 2.5 days to provide 3.1 g of 7-methoxyquinolin-4-ol as a light tan solid.

後処理

  1. temperaturewas heated
  2. temperatureat reflux for 2 hrs
  3. customThe resulting precipitate was isolated by filtration
  4. customdried in a vacuum oven at 80° C. for 2.5 days

出典と根拠

ORDレコード
ord-0f2302e84a904c439d868abfbb7436ce
出典データセット
uspto-grants-2004_03
特許番号
US06703402B2

関連ノート

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