化工社化工社 化学情報印刷レポート · 研究参考用
Dimethyl Sulfoxide → 2-trifluoromethylphenyl-S,S-dimethylsulfilimine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethyl Sulfoxide | HCID 679 | — |
| 反応物 | 2-Nitro-alpha,alpha,alpha-trifluorotoluene | HCID 9795 | — |
| 反応物 | 2-(Trifluoromethyl)phenyl isocyanate | HCID 16794 | — |
| 生成物 | 2-trifluoromethylphenyl-S,S-dimethylsulfilimine | HCID 13391192 | — |
反応手順
The process of claim 18 in which 2-trifluoromethylnitrobenzene is carbonylated to 2-trifluoromethylphenyl isocyanate, which is reacted with dimethylsulfoxide to obtain N-(2-trifluoromethylphenyl)-S,S-dimethylsulfilimine, rearranged to a 2-(methylthiomethyl)-6-trifluoromethylaniline, and desulfurized to 2-methyl-6-trifluoromethyl aniline.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04578514 |
| 出典データセット | uspto-grants-1986_03 |
| ORD ID | ord-564a0531b1c74f918c075c91dda58357 |
| 出典メモ | uspto-grants-1986_03 |