関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Methacrylic Acid | HCID 4093 | — |
| 反応物 | 3,4-dihydro-2H-pyran | HCID 8080 | — |
| 反応物 | Sodium Bicarbonate | HCID 516892 | — |
| 触媒 | Hydrochloric Acid | HCID 313 | — |
| 触媒 | 2,4-Dinitrotoluene | HCID 8461 | — |
| 生成物 | Tetrahydropyranyl methacrylate | HCID 11041138 | 91% |
反応手順
to a solution of 25.8 g (0.3 mol) methacrylic acid and 1.8 g (0.011 mol) 2,4-dinitrotoluene in 25.2 g (0.3 mol) dihydropyran was added 0.05 ml (0.0015 mol) concentrated hydrochloric acid. The reaction mixture was allowed to stir at 50° C. for 25 hr. The hydrochloric acid was neutralized with solid sodium bicarbonate and the mixture was filtered. The filtrate was distilled to give 46.5 g (0.273 mol, 91% yield) tetrahydropyran-2-yl methacrylate, bp 50° C. at 0.15 torr.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05225316 |
|---|
| 出典データセット | uspto-grants-1993_07 |
|---|
| ORD ID | ord-a4b22e8e27be4e7fb3eadcb1543bfa82 |
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| 出典メモ | uspto-grants-1993_07 |
|---|
