反応式
[CH2:1]([O:3][P:4]([CH:9]=[C:10]1[NH:16][CH2:15][CH2:14][N:13]([CH3:17])[C:12]2[CH:18]=[CH:19][CH:20]=[CH:21][C:11]1=2)(=[O:8])[O:5][CH2:6][CH3:7])[CH3:2].[F:22]C1C=C(F)C=CC=1C(O)=O>>[CH2:1]([O:3][P:4]([CH:9]=[C:10]1[NH:16][CH2:15][CH2:14][N:13]([CH3:17])[C:12]2[CH:18]=[C:19]([F:22])[CH:20]=[CH:21][C:11]1=2)(=[O:8])[O:5][CH2:6][CH3:7])[CH3:2]参加物
3
実験手順
The starting material (8-fluoro-1-methyl-1,2,3,4-tetrahydrobenzo[e][1,4]-diazepin-5-ylidenemethyl)phosphonic acid diethyl ester was prepared in an analogous fashion to (1-methyl-1,2,3,4-tetrahydrobenzo[e][1,4]diazepin-5-ylidenemethyl)phosphonic acid diethyl ester, as described in Example 1 by replacing 2-fluorobenzoic acid with 2,4-difluorobenzoic acid.
出典と根拠
- ORDレコード
- ord-abc16f3cc58d4f7da8d4f0a457a7dbba
- 出典データセット
- uspto-grants-2004_03
- 特許番号
- US06703387B2
関連ノート
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