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2,5-Dichlorophenol → 2,5-Dichlorophenyl Dimethyloctylsilyl Ether
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,5-Dichlorophenol | HCID 66 | — |
| 反応物 | Imidazole | HCID 795 | — |
| 反応物 | Chlorodimethyloctylsilane | HCID 87482 | — |
| 溶媒 | Sodium Chloride | HCID 5234 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 2,5-Dichlorophenyl Dimethyloctylsilyl Ether | HCID 53988840 | — |
反応手順
To a solution of 3.75 g (0.023 mole) 2,5-dichlorophenol in 30 ml N,N-dimethylformamide are added 5.58 g (0.082 mole) imidazole and 16.6 ml (0.070 mole) chlorodimethyloctyl silane under argon. After stirring at room temperature for two hours, the mixture is diluted with an aqueous saturated sodium chloride solution and extracted with ether. The combined organic extracts are dried and condensed. The product is purified by column chromatography.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05227457 |
| 出典データセット | uspto-grants-1993_07 |
| ORD ID | ord-3d90883c40d24a52b08099e78da52c02 |
| 出典メモ | uspto-grants-1993_07 |