化工社化工社 化学情報印刷レポート · 研究参考用
Sulfolane → 2,4-Difluorobenzaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfolane | HCID 31347 | — |
| 反応物 | 2-Chloro-4-fluorobenzaldehyde | HCID 145024 | — |
| 反応物 | Potassium Fluoride | HCID 522689 | — |
| 反応物 | 4-Chloro-2-fluorobenzaldehyde | HCID 2724908 | — |
| 生成物 | 2,4-Difluorobenzaldehyde | HCID 73770 | — |
反応手順
158.5 g (1 mol) of a mixture of 56% of 4-chloro-2-fluoro-benzaldehyde and 44% of 2-chloro-4-fluorobenzaldehyde were heated together with 700 g of sulfolane and 75 g (1.29 mol) of potassium fluoride at 215° C. for 10 h. The working up was carried out as in Example 1. 99.5 g of 2,4-difluorobenzaldehyde equivalent to 70% of the feed-stock was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05227531 |
| 出典データセット | uspto-grants-1993_07 |
| ORD ID | ord-6c1a97fab7104349a0387170691bc375 |
| 出典メモ | uspto-grants-1993_07 |