化工社化工社 化学情報印刷レポート · 研究参考用
1,3,4,9-Tetrahydro-1,1-diethyl-6-(phenylmethoxy)pyrano[3,4-b]indole → 1,3,4,9-Tetrahydro-1,1-diethyl-6-(hydroxy)pyrano[3,4-b]indole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,3,4,9-Tetrahydro-1,1-diethyl-6-(phenylmethoxy)pyrano[3,4-b]indole | HCID 19935702 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 1,3,4,9-Tetrahydro-1,1-diethyl-6-(hydroxy)pyrano[3,4-b]indole | HCID 19935698 | 109.8% |
反応手順
A mixture consisting of 10% Pd/c on charcoal (1.0 g), ethanol (125 mL), and 1,3,4,9-tetrahydro-1,1-diethyl-6-(phenylmethoxy)pyrano[3,4-b]indole (6.5 g, 0.0193 mol), of Step A, is hydrogenated at 30 psi for 18 hours. The reaction mixture is filtered and concentrated to give 5.2 g of product which is used in the next reaction without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05229516 |
| 出典データセット | uspto-grants-1993_07 |
| ORD ID | ord-9bd569f7b3ff4c85be7cc8ea789a80b4 |
| 出典メモ | uspto-grants-1993_07 |